# When hepatitis B has progressed to cirrhosis: follow-up, complications, and emergency signs URL: https://openhbv.bangbo.dev/articles/when-hepatitis-b-has-progressed-to-cirrhosis-follow-up-complications-and-emergency-signs?locale=en Canonical Markdown: https://openhbv.bangbo.dev/articles/when-hepatitis-b-has-progressed-to-cirrhosis-follow-up-complications-and-emergency-signs.md?locale=en Language: en Translation key: article-ec1cc9c91667 Topic: 治疗与随访 Audience: Patients and families Region: Global Published: 2026-06-26 Last reviewed: 2026-06-26 Review status: source_backed Tags: 治疗, 随访监测, 指南 ## Summary A practical guide for people told they have cirrhosis or advanced fibrosis: antiviral care, cancer surveillance, varices, ascites, medicine safety, nutrition, and emergency signs. ## Article ## First clarify compensated or decompensated cirrhosis Cirrhosis is not a single-risk label. Clinicians may use platelets, albumin, bilirubin, INR, creatinine, ascites, variceal bleeding, hepatic encephalopathy, imaging, and elastography to decide whether cirrhosis is compensated or decompensated. Compensated cirrhosis may have few symptoms but still needs regular follow-up. Decompensation means higher risk and may require closer care or liver transplant evaluation. ## Hepatitis B still needs active management People with HBV-related cirrhosis should not focus only on liver-protective supplements or transaminases. Clinicians usually review HBV DNA, ALT/AST, HBeAg/anti-HBe, kidney function, bone risk, and past medicines to decide whether antivirals are needed or should continue. Do not stop entecavir, TDF, or TAF because HBV DNA is temporarily undetectable or ALT is normal. ## Four complications to ask about First, liver cancer surveillance. Chronic hepatitis B with cirrhosis usually places a person in a group needing regular surveillance, often ultrasound plus AFP at about 6-month intervals when appropriate. Second, esophageal or gastric varices and bleeding risk. Ask whether endoscopy or another assessment is needed and whether medicine or endoscopic treatment could reduce bleeding risk. Vomiting blood, black tarry stools, dizziness, or fainting should be treated urgently. Third, ascites and swelling. Rapidly increasing abdominal size, leg swelling, fever with abdominal pain, reduced urination, or shortness of breath should prompt medical contact. Do not self-treat with large diuretic doses, extreme water restriction, or salt changes. Fourth, hepatic encephalopathy. Reversed sleep pattern, slower responses, confused speech, personality change, marked sleepiness, or confusion can be danger signs. Family members should not dismiss these changes as simple tiredness or mood. ## Daily records help care decisions Cirrhosis does not automatically mean only porridge or bed rest. Many people need enough protein and energy to avoid muscle loss, but ascites, kidney problems, diabetes, or encephalopathy risk can change the plan. Ask for individualized advice about salt, protein, fluids, and activity. Record weight, abdominal circumference, leg swelling, urine changes, appetite, sleep, alertness, medicines, and alcohol. These notes help clinicians judge ascites, kidney function, and encephalopathy risk better than saying everything is fine. ## When to seek urgent care Seek urgent care for vomiting blood, black stools, confusion, marked sleepiness, rapid abdominal swelling, fever with abdominal pain, worsening jaundice, clearly reduced urination, severe fatigue, persistent vomiting, breathing difficulty, or unexplained falls. If you have cirrhosis, these symptoms should not wait for the next routine appointment. ## Action checklist Keep the reports that support the cirrhosis diagnosis and staging. Track HBV DNA, ALT/AST, bilirubin, albumin, INR, platelets, creatinine, ultrasound, and AFP. Confirm the next liver cancer surveillance date. Ask whether endoscopy or variceal management is needed. Record weight, abdominal size, swelling, sleep, and mental status. Do not stop antivirals or use herbs on your own. Seek care quickly for bleeding, confusion, rapid swelling, or low urine output. ## References 1. VA Cirrhosis Patient Guide Organization: U.S. Department of Veterans Affairs Source page: https://openhbv.bangbo.dev/sources/va-cirrhosis-patient-guide?locale=en Original URL: https://www.hepatitis.va.gov/cirrhosis/patient/single-page.asp Source type: patient_resource Accessed: 2026-06-26 2. NIDDK Cirrhosis Symptoms and Causes Organization: National Institute of Diabetes and Digestive and Kidney Diseases Source page: https://openhbv.bangbo.dev/sources/niddk-cirrhosis-symptoms-and-causes?locale=en Original URL: https://www.niddk.nih.gov/health-information/liver-disease/cirrhosis/symptoms-causes Source type: patient_resource Accessed: 2026-06-26 3. Hepatitis B Foundation Cirrhosis Organization: Hepatitis B Foundation Source page: https://openhbv.bangbo.dev/sources/hepatitis-b-foundation-cirrhosis?locale=en Original URL: https://www.hepb.org/treatment-and-management/adults-with-hepatitis-b/cirrhosis/ Source type: patient_resource Accessed: 2026-06-26 4. AASLD Practice Guidance on Prevention, Diagnosis, and Treatment of Hepatocellular Carcinoma Organization: American Association for the Study of Liver Diseases Source page: https://openhbv.bangbo.dev/sources/aasld-practice-guidance-on-prevention-diagnosis-and-treatment-of-hepatocellular-carcinoma?locale=en Original URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10663390/ Source type: guideline Accessed: 2026-06-26 5. WHO 2024 Chronic Hepatitis B Guidelines Organization: World Health Organization Source page: https://openhbv.bangbo.dev/sources/who-2024-chronic-hepatitis-b-guidelines?locale=en Original URL: https://www.who.int/publications/i/item/9789240090903 Source type: guideline Accessed: 2026-06-26 ## Use And Safety Notes This Markdown version is provided for search, retrieval, and LLM citation workflows. OpenHBV is a health education site, not a personal diagnosis or treatment service. Use the references above to verify medical claims, and consult qualified clinicians for individual decisions.